{"id":7178,"date":"2022-01-11T18:51:35","date_gmt":"2022-01-11T13:21:35","guid":{"rendered":"https:\/\/polscienceweb.com\/?post_type=portfolio&#038;p=7178"},"modified":"2022-01-11T18:57:02","modified_gmt":"2022-01-11T13:27:02","slug":"worlds-first-pig-to-human-heart-transplant-successfully-tested","status":"publish","type":"portfolio","link":"https:\/\/polscienceweb.com\/index.php\/portfolio\/worlds-first-pig-to-human-heart-transplant-successfully-tested\/","title":{"rendered":"World&#8217;s first pig to human heart transplant successfully tested"},"content":{"rendered":"\n<h4 class=\"has-text-align-center wp-block-heading\">The breakthrough, if proven successful, may become the solution to solve organ shortages for transplants<\/h4>\n\n\n<div class=\"has-text-align-center wp-block-post-date\"><time datetime=\"2022-01-11T18:51:35+05:30\">11th January 2022<\/time><\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<details class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">\n<summary class=\"wo-block-verse\" style=\"font-size: 18px; text-align: center;\">Read more<br><br><\/summary>\n\n\n\n<p class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">In a first-of-its-kind procedure, David Bennett, a 57-year-old man from the United States with fatal heart disease, was implanted with a <strong>genetically modified pig heart<\/strong>. He is still doing well, as per the doctors; three days after the historic surgery,&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">A team from the University of Maryland Medicine carried out the procedure. It is the <strong>first to show that a heart transplant from pig to human is feasible <\/strong>and made possible through new <strong><a href=\"https:\/\/polscienceweb.com\/index.php\/2020\/12\/27\/crispr\/\" target=\"_blank\" rel=\"noreferrer noopener\">gene-editing techniques<\/a><\/strong>. Scientists anticipate that, if proven successful, pig organs will assist in reducing donor organ shortages.<\/p>\n\n\n\n<p class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">The scarcity of organs is one of the greatest challenges confronting the transplant field today. Only a few patients with end-stage heart disease receive a transplant, and many die while waiting for a new organ. <strong>Xenotransplantation<\/strong> (transplantation between species) might solve this acute scarcity.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">Pigs have long been a promising source of possible transplants because their organs are comparable to humans. A pig heart is roughly the size of an adult human heart at the time of slaughter. Attempts at pig-to-human transplants had previously failed due to genetic differences resulting in <strong>organ rejection or infections<\/strong> caused due to viruses. Scientists have found a solution to this dilemma by removing possibly dangerous genes.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">In the heart placed in Bennett, three genes previously related to organ rejection were &#8220;knocked out&#8221; of the donor pig&#8217;s genome, while six human genes linked to immune acceptance were reintroduced in it. Researchers also removed a gene to avoid the excessive development of pig heart tissue.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-verse\" style=\"font-size: 18px; text-align: justify;\">Other pig organs studied<strong> <\/strong>for transplantation into humans include <strong>kidneys, liver, and lungs.<\/strong> Previously, doctors in the United States had also successfully transplanted a pig&#8217;s kidney into a brain-dead individual who was already on artificial life support and had little chance of recovery.<\/p>\n\n\n\n<\/details>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-center\">Source: <a href=\"https:\/\/www.nytimes.com\/2022\/01\/10\/health\/heart-transplant-pig-bennett.html\" target=\"_blank\" rel=\"noreferrer noopener\">NYTimes<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The breakthrough, if proven successful, may become the solution to solve organ shortages for transplants&hellip;<\/p>\n","protected":false},"author":1,"featured_media":7182,"comment_status":"closed","ping_status":"closed","template":"","portfolio-category":[428,430,426],"class_list":["post-7178","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry","portfolio-category-428","portfolio-category-january-2022","portfolio-category-newsfeed"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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